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Animal models for medical countermeasures to radiation …

    https://pubmed.ncbi.nlm.nih.gov/20334528/
    A network of Centers for Medical Countermeasures against Radiation (CMCRs) has been established across the U.S.; one of the missions of this network is to identify and develop mitigating agents that can be used to treat the civilian population after a radiological event.

Animal Models for Medical Countermeasures to …

    https://meridian.allenpress.com/radiation-research/article/173/4/557/43020/Animal-Models-for-Medical-Countermeasures-to
    The most widely used and well-characterized end point for the assessment of acute hematopoietic radiation damage after TBI is the LD 50, measured over the …

Opportunities and challenges with animal models for …

    https://www.tandfonline.com/doi/full/10.1080/17460441.2018.1526172
    The criteria of the FDA’s Animal Rule relevant to development using animal models are as ...

Animal Models for Medical Countermeasures to …

    https://www.researchgate.net/publication/42540722_Animal_Models_for_Medical_Countermeasures_to_Radiation_Exposure
    Large and small animal models have been proposed for this purpose and used extensively following the Animal rule 25, 26 to study responses at longer times after …

Animal models for acute radiation syndrome drug discovery

    https://pubmed.ncbi.nlm.nih.gov/25819367/
    Abstract. Introduction: Although significant scientific advances have been made over the past six decades in developing safe, nontoxic and effective radiation/medical …

Animal models for acute radiation syndrome drug discovery

    https://www.tandfonline.com/doi/full/10.1517/17460441.2015.1023290
    Mar 27, 2015

Animal Models for Medical Countermeasures to …

    https://www.semanticscholar.org/paper/Animal-Models-for-Medical-Countermeasures-to-Williams-Brown/f5de9fbbef458b871ac1d17d003acb87c8fe6b7b
    Investigators from each of the CMCRs organized and met for an Animal Models Workshop, which discussed the wide range of animal models available for …

Animal Models and Medical Countermeasures …

    https://meridian.allenpress.com/radiation-research/article/177/5/e0025/150094/Animal-Models-and-Medical-Countermeasures
    An alternative protocol, proposed as part of a CMCR animal models workshop ( 60 ), is to expose the animals to a sub-lethal TBI radiation exposure, but …

Animal Models for Medical Countermeasures to …

    https://www.academia.edu/56974818/Animal_Models_for_Medical_Countermeasures_to_Radiation_Exposure
    Animal Models for Medical Countermeasures to Radiation Exposure Jacqueline P. Williams,a,1 Stephen L. Brown,b George E. Georges,c Martin Hauer-Jensen,d Richard P. …

Radiological and nuclear emergency preparedness - FDA

    https://www.fda.gov/emergency-preparedness-and-response/mcm-issues/radiological-and-nuclear-emergency-preparedness-information-fda
    November 28, 2022: FDA approved a new indication (PDF, 244 KB) for Udenyca (pegfilgrastim-cbqv) to increase survival of adult and pediatric patients acutely exposed to …



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