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Use of Osmotic Pumps to Establish the Pharmacokinetic …

    https://pubmed.ncbi.nlm.nih.gov/27194201/
    The development of reliable relationships between in vivo target engagement, pharmacodynamic activity, and efficacy in chronic disease models is beneficial for enabling hypothesis-driven drug discovery and facilitating the development …

Osmosis and Its Applications | SpringerLink

    https://link.springer.com/referenceworkentry/10.1007/978-3-642-27758-0_1741-1
    The second application is utilized to control the drug release in terms of dosage and dosing frequency so that the bioavailability can be enhanced and the side …

Use of Osmotic Pumps to Establish the …

    https://pubs.acs.org/doi/10.1021/acs.jmedchem.6b00398
    Use of Osmotic Pumps to Establish the Pharmacokinetic–Pharmacodynamic Relationship and Define Desirable Human Performance Characteristics for Aggrecanase Inhibitors …

Osmotic Pump - an overview | ScienceDirect Topics

    https://www.sciencedirect.com/topics/nursing-and-health-professions/osmotic-pump
    To maintain an effective NaCl concentration within the drug compartment over the release duration, NaCl granules were coated with a microporous cellulose acetate butyrate 381 …



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