Diseases With Unmet Medical Need

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Unmet Medical Needs Persist Across Many Diseases

https://www.forbes.com/sites/joshuacohen/2018/12/26/unmet-medical-needs-persist-across-many-diseases/

There is enduring unmet need across multiple diseases that disproportionately impact women, including autoimmune disorders, chronic pain conditions, endometriosis, uterine fibroids,...

Unmet medical need - National Institutes of Health

https://toolkit.ncats.nih.gov/glossary/unmet-medical-need/

An unmet medical need is a condition or symptom whose treatment or diagnosis is not addressed adequately by available therapy. An unmet medical need includes an …

Unmet Medical Need: An Introduction to Definitions and …

https://pubmed.ncbi.nlm.nih.gov/31708064/

Background: Despite increasing informal and formal use of unmet medical need (UMN) in drug development, regulation, and assessment, there is no insight into its definitions …

Unmet medical need - EFPIA

https://efpia.eu/about-medicines/development-of-medicines/unmet-medical-need/

Unmet medical need should help to shape policy and action from early phase research, through clinical development to pricing and reimbursement to how a new medicine …

Unmet medical need - European Medicines Agency

https://www.ema.europa.eu/en/documents/presentation/presentation-defining-unmet-medical-need-jstokx_en.pdf

“Unmet medical needs means a condition for which there exists no satisfactory method of diagnosis, prevention or treatment in the Union or, even if such a method exists, …

Disease Areas: Addressing Unmet Needs - Insmed

https://insmed.com/patients/disease-areas/

Nontuberculous mycobacterial (NTM) lung disease is a rare and serious disorder most commonly caused by a group of bacteria in the environment called Mycobacterium …

Unmet Medical Needs in Chronic, Non-communicable …

https://pubmed.ncbi.nlm.nih.gov/35755063/

The autoimmune response may be mainly T cell driven, such as in alopecia areata or vitiligo, or B cell driven in chronic spontaneous urticaria, pemphigus and …

Antibacterial Therapies for Patients With an Unmet …

https://www.fda.gov/regulatory-information/search-fda-guidance-documents/antibacterial-therapies-patients-unmet-medical-need-treatment-serious-bacterial-diseases

Antibacterial Therapies for Patients With an Unmet Medical Need for the Treatment of Serious Bacterial Diseases GUIDANCE DOCUMENT Antibacterial …

Major unmet needs in the cardiovascular area - OUP …

https://academic.oup.com/eurheartjsupp/article/20/suppl_C/C4/4965067

In absence of new ideas, CV research will provide ‘Me-too agents’, small incremental advances and repurposing therapies. 18 Therefore, we need to move away …

Pembrolizumab Could Meet Unmet Need in BCG …

https://www.cancertherapyadvisor.com/home/news/conference-coverage/american-society-of-clinical-oncology-genitourinary-asco-gu/asco-gu-2023/pembrolizumab-nmibc-high-risk-bcg-unresponsive-unmet-need/

2 hours ago · The median DFS was 6.0 months for any disease (defined as low-grade Ta, high-risk disease, and progressive disease). This DFS rate was 41.7% at 12 months and …

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