Galectin 3 Medical Policy

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MEDICAL POLICY - GALECTIN-3 TESTING IN THE …

https://www.bcbsm.com/amslibs/content/dam/public/mpr/mprsearch/pdf/2029170.pdf

Galectin-3 is a beta-galactoside-binding protein that is associated with inflammation, fibrosis, and cardiac remodeling. Increased levels of galectin-3 have been found in individuals with acutely decompensating heart failure. There is interest in whether …

Galectin-3, a rising star in modulating microglia activation …

https://www.nature.com/articles/s41419-022-05058-3

Galectin-3 (Gal-3) is a pleiotropic protein that binds to β-galactoside residues present in glycoproteins. Gal-3 is mainly expressed and released in the damaged brain …

Galectin-3: a key player in microglia-mediated ... - PubMed

https://pubmed.ncbi.nlm.nih.gov/33906678/

1 Department of Neurology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China. ... One of the key …

Efficacy of serum apelin and galectin‐3 as potential …

https://onlinelibrary.wiley.com/doi/10.1002/jmv.28494?af=R

When the threshold value for galectin-3 was regarded as 2.8 ng/ml, it was discovered to predict mortality with 80% sensitivity and 57% specificity (area under the …

Galectin-3 | Test Detail | Quest Diagnostics

https://testdirectory.questdiagnostics.com/test/test-detail/92768/galectin-3?cc=MASTER

Galectin-3 - A galectin-3 test may be ordered for the identification of individuals with chronic heart failure at elevated risk of disease progression. ... Test Code. 92768. CPT …

Galectin-3 regulates microglial activation and promotes …

https://pubmed.ncbi.nlm.nih.gov/35121106/

Galectin-3, an attractive molecule of innate immunity, has been reported to be involved in the neuroinflammatory diseases. However, the role of Galectin-3 in autoimmune uveitis …

Galectin-3: Disarming Cancer’s …

https://draxe.com/health/galectin-3/

Galectin-3 allows tumor cells to stick together, develop blood supply, metastasize and evade the immune system. Galectin-3 also prevents apoptosis of cancer cells, and forms a protective …

Galectin-3 is involved in fibrotic disease and cancer

https://galectintherapeutics.com/about-galectin-3/

Galectin-3 at the root of fibrotic disease, including liver fibrosis and NASH cirrhosis. ... Medical science is recognizing the role that galectin-3 plays in a wide range of diseases. …

Pathology Outlines - Galectin3

https://www.pathologyoutlines.com/topic/stainsgalectin3.html

Definition / general. Member of carbohydrate-binding protein family known as lectins. One of 14 galectins, which function as cell receptors for N-acetyl-lactosamine moieties present on most …

Galecto Publishes Results Showing Safety and Efficacy of

https://www.globenewswire.com/news-release/2022/01/27/2374172/0/en/Galecto-Publishes-Results-Showing-Safety-and-Efficacy-of-the-GB0139-Inhaled-Galectin-3-Inhibitor-in-Hospitalized-COVID-19-Patients-on-Standard-of-Care.html

The research article is titled “GB0139, an inhaled small molecule inhibitor of galectin-3, in COVID-19 pneumonitis: A randomised, controlled, open-label, Phase 2a …

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