Humane Endpoints For Animals Used In Biomedical Research

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Guidelines for Endpoints in Animal Study Proposals

https://oacu.oir.nih.gov/system/files/media/file/2022-04/b13_endpoints_guidelines.pdf

Where pain or distress is a necessary part of the study, a humane endpoint must be used and approved by the ACUC.1 A humane endpoint is the earliest scientifically justified point at which pain or distress in an experimental animal can be prevented, terminated, or …

Humane Endpoints | Research at Penn State

https://www.research.psu.edu/animalresourceprogram/experimental-guidelines/humane-endpoints

Humane Endpoints in Animal Research | Research at …

https://www.research.psu.edu/newanimal/experimental-guidelines/defining-humane-endpoints

Humane endpoints refer to one or more predetermined physiological or behavioral signs that define the point at which an experimental animal’s pain and/or distress is terminated, …

Volume 41 Issue 2 | ILAR Journal | Oxford Academic

https://academic.oup.com/ilarjournal/issue/41/2

Humane Endpoints for Infectious Disease Animal Models Ernest D. Olfert, Dale L. Godson ILAR Journal, Volume 41, Issue 2, 2000, Pages 99–104, …

How to determine humane endpoints for …

https://www.nature.com/articles/laban.908

This public material also explains some of the important areas of research wherein animal models are used—cancer, toxicity studies, vaccine potency, …

A review on humane endpoints in animal …

https://www.researchgate.net/publication/351152326_A_review_on_humane_endpoints_in_animal_experimentation_for_biomedical_research

Results: "Humane endpoints" or killing the animal humanely means the point at which an experimental animal's pain and/or distress is terminated. This pain and …

Humane endpoints in animal …

https://www.researchgate.net/publication/228604657_Humane_endpoints_in_animal_experimentation_for_biomedical_research_ethical_legal_and_practical_aspects

According to the guidelines regulated by the Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA) (1960), experiments …

Humane Endpoints for Laboratory Animals Used in …

https://academic.oup.com/ilarjournal/article/43/Suppl_1/S31/756764

Humane Endpoints for Acute and Chronic Toxicity Testing Acute Lethality Testing. Acute lethality testing is performed to estimate the dose expected to kill half of …

Humane endpoints in animal experiments for biomedical …

https://www.semanticscholar.org/paper/Humane-endpoints-in-animal-experiments-for-research-Hendriksen-Morton/39a90f6d94c0880b9eb32f49e7d132768eb3dbc0

The history of animal use in biomedical research, some of its main protagonists and antagonists, and its effect on society from Antiquity to the present day is addressed, …

Humane Endpoints in Shock Research : Shock - LWW

https://journals.lww.com/shockjournal/Pages/articleviewer.aspx?year=2004&issue=01000&article=00004&type=Fulltext

In biomedical research using animal models, the phrase “humane endpoints” refers to predetermined criteria used to judge when the research animals should be …

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