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How does the liver work?

    https://www.ncbi.nlm.nih.gov/books/NBK279393/

    Drug Metabolism - Drugs - Merck Manuals …

      https://www.merckmanuals.com/home/drugs/administration-and-kinetics-of-drugs/drug-metabolism

      Drug Metabolism - Clinical Pharmacology - Merck …

        https://www.merckmanuals.com/professional/clinical-pharmacology/pharmacokinetics/drug-metabolism
        Drugs can be metabolized by oxidation, reduction, hydrolysis, hydration, conjugation, condensation, or isomerization; whatever the process, the goal is to make the drug easier …

      Drug Metabolism - Drugs - MSD Manual Consumer Version

        https://www.msdmanuals.com/home/drugs/administration-and-kinetics-of-drugs/drug-metabolism
        Most drugs must pass through the liver, which is the primary site for drug metabolism. Once in the liver, enzymes convert prodrugs to active metabolites or convert active …

      Drug Metabolism in the Liver - University of Washington

        https://courses.washington.edu/medch527/PDFs/Literature/527_2017_drugMetabLiver.pdf
        Drug metabolism typically results in the formation of a more hydrophilic compound that isreadily excreted by the liver, kidney, and/or gut. Drug metabolism involves chemical …

      Drug Metabolism in the Liver - PubMed

        https://pubmed.ncbi.nlm.nih.gov/27842765/
        Phase III refers to transporter-mediated elimination of drug and/or metabolites from body normally via liver, gut, kidney, or lung. This review presents basic information on drug …

      Kidney and liver clearance | Medicines …

        https://www.medicineslearningportal.org/2015/07/kidney-and-liver-clearance.html
        Three processes determine the amount of drug cleared by the kidneys: glomerular filtration, active tubular secretion and passive tubular reabsorption. …

      Circulation through the liver in light of drug metabolism

        https://biology.stackexchange.com/questions/2973/circulation-through-the-liver-in-light-of-drug-metabolism
        The portal vein is part of the portal system and connects the capillary beds of the gastrointestinal tract to those of the liver. Because of the larger volume through the …

      How Does The Body Metabolize …

        https://ocrc.net/how-does-the-body-metabolize-medication/
        When the human body begins to metabolize a medication, different organs process the ingredients before they are finally released in the …

      Do compounds absorbed through the skin bypass the liver?

        https://medicalsciences.stackexchange.com/questions/7008/do-compounds-absorbed-through-the-skin-bypass-the-liver
        Although the plasma concentration-time profiles of metabolites may differ after oral and parenteral doses, the fraction of a dose eventually converted to a metabolite …



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