Krabbe Disease Medical Articles

Krabbe Disease - National Institute of Neurological …

https://www.ninds.nih.gov/health-information/disorders/krabbe-disease

Krabbe disease is caused by a defect in the GALC gene, leading to malfunction of galactocerebrosidase, an essential enzyme for myelin metabolism, and consequent accumulation of a toxic myelin breakdown product. The disease most often …

Krabbe Disease - StatPearls - NCBI Bookshelf

https://www.ncbi.nlm.nih.gov/books/NBK562315/

Krabbe disease, an autosomal recessive disease, is a type of lysosomal storage disorder that …

Krabbe Disease: What It Is, Diagnosis, Symptoms

https://my.clevelandclinic.org/health/diseases/6039-krabbe-disease-globoid-cell-leukodystrophy

Most people with late-onset Krabbe disease deteriorate both mentally and physically. What causes Krabbe disease? Krabbe disease is a hereditary condition passed on to …

Krabbe disease: Treatment, causes and diagnosis

https://www.medicalnewstoday.com/articles/krabbe-disease

Krabbe disease is a rare genetic disorder in which a person lacks an enzyme that breaks down specific lipids. The lipid buildup progressively destroys the …

Krabbe Disease: Causes, Symptoms & Diagnosis

https://www.healthline.com/health/krabbe-disease

Krabbe disease: MedlinePlus Genetics

https://medlineplus.gov/genetics/condition/krabbe-disease/

Krabbe disease (also called globoid cell leukodystrophy) is a severe neurological condition. It is part of a group of disorders known as leukodystrophies, which result from …

Krabbe disease - About the Disease - Genetic and Rare …

https://rarediseases.info.nih.gov/diseases/6844/krabbe-disease/

Krabbe disease affects the development and function of the nervous system. There are several types of Krabbe disease that differ based on the age that symptoms begin. …

Krabbe disease: MedlinePlus Medical Encyclopedia

https://medlineplus.gov/ency/article/001198.htm

Krabbe disease is a rare genetic disorder of the nervous system. It is a type of brain disease called leukodystrophy. Causes A defect in the GALC gene causes Krabbe …

Krabbe disease: A personal perspective and hypothesis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783082/

Introduction: Krabbe disease (KD) or globoid cell leukodystrophy (GLD) is one of the lysosomal disorders affecting central and peripheral nervous systems (CNS …

Krabbe disease | Radiology Reference …

https://radiopaedia.org/articles/krabbe-disease

Citation, DOI & article data Epidemiology. The majority of individuals with Krabbe disease present in early childhood although adult presentations as... Clinical …