Mechanisms Of Medical Castration By Lhrh Agonists

Hormone Therapy for Prostate Cancer Fact Sheet - NCI

https://www.cancer.gov/types/prostate/prostate-hormone-therapy-fact-sheet

Four LHRH agonists are approved to treat prostate cancer in the United States: leuprolide (Lupron), goserelin (Zoladex), triptorelin (Trelstar), and histrelin (Vantas). When patients receive an LHRH agonist for the first time, they may experience a phenomenon …

Medical Castration With LHRH Agonists: 25 Years Later …

https://onlinelibrary.wiley.com/doi/full/10.1002/j.1939-4640.2004.tb02791.x

The availability of a safe and highly efficient method of medical castration with LHRH agonists free of the side effects of estrogens and surgical castration has …

Mode of Action of LHRH Analogs - Holland …

https://www.ncbi.nlm.nih.gov/books/NBK12517/

LHRH analogs are widely used in oncology, and their mode of action is almost completely understood. The …

Luteinizing hormone-releasing hormone (LHRH) receptor …

https://pubmed.ncbi.nlm.nih.gov/23418666/

Luteinizing hormone-releasing hormone (LHRH) agonists and antagonists are commonly used androgen deprivation therapies prescribed for patients with advanced prostate …

Chemically Castrating: How It Works, Uses, and Side …

https://www.healthline.com/health/chemically-castrating

Oral Relugolix for Androgen-Deprivation …

https://www.nejm.org/doi/full/10.1056/NEJMoa2004325

The development of safe and effective GnRH antagonists has proved to be difficult 19; hence, LHRH agonists were developed. When administered on a long …

The Role of LHRH Antagonists in the Treatment of …

https://www.cancernetwork.com/view/role-lhrh-antagonists-treatment-prostate-cancer

Currently available LHRH agonists include leuprolide, goserelin (Zoladex), buserelin, and triptorelin (Trelstar). Available in various formulations, these drugs are …

Medical Castration With LHRH Agonists: 25 Years Later …

https://www.researchgate.net/publication/8637906_Medical_Castration_With_LHRH_Agonists_25_Years_Later_With_Major_Benefits_Achieved_on_Survival_in_Prostate_Cancer

The growth of primary prostate cancer (PC) is dependent on androgens (1). Androgen ablation therapy through chemical castration with a luteinizing hormone …

[Chemical castration using a depot LHRH-agonist as a …

https://pubmed.ncbi.nlm.nih.gov/2148044/

79 patients with locally advanced and/or metastatic prostate cancer were treated by means of a biodegradeable depot formulation of the luteinizing hormone …

What is medical castration?

https://www.news-medical.net/health/What-is-medical-castration.aspx

Medical castration – Sometimes surgery may not be acceptable or possible. In these cases, certain drugs are used to suppress androgens and this form of treatment …