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Sildenafil Citrate Therapy for Pulmonary Arterial …

    https://www.nejm.org/doi/full/10.1056/NEJMoa050010
    In this double-blind, placebo-controlled study, we randomly assigned 278 patients with symptomatic pulmonary arterial hypertension (either idiopathic or associated with …

Sildenafil in Pulmonary Arterial Hypertension | American …

    https://www.atsjournals.org/doi/full/10.1164/ajrccm.169.11.958
    Only sildenafil obtained a significant reduction of mean pulmonary arterial pressure from 71.4 to 57 mm Hg (−20%) and pulmonary vascular resistance from 1,333 to 843 …

Pulmonary hypertension - Diagnosis and treatment

    https://www.mayoclinic.org/diseases-conditions/pulmonary-hypertension/diagnosis-treatment/drc-20350702

    Sildenafil - StatPearls - NCBI Bookshelf

      https://www.ncbi.nlm.nih.gov/books/NBK558978/
      Sildenafil is a medication used in the management and treatment of erectile dysfunction and …

    Sildenafil for Pulmonary Arterial Hypertension - CHEST

      https://journal.chestnet.org/article/S0012-3692(15)32508-3/fulltext
      Sildenafil for Pulmonary Arterial Hypertension Pulmonary arterial hypertension (PAH) is a serious, often fatal condition. The clinical hallmarks are progressive breathlessness, …

    Sildenafil in Primary Pulmonary Hypertension | NEJM

      https://www.nejm.org/doi/full/10.1056/NEJM200011023431814
      A recent study in children suggested a potential role for sildenafil in the management of pulmonary hypertension. 2,3 Sildenafil may preferentially inhibit cGMP …

    Sildenafil protects against pulmonary hypertension …

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722768/
      Persistent pulmonary hypertension of the newborn (PPHN) is a common pulmonary vascular disease during the neonatal period, and it is associated with a high …

    Sildenafil for Pulmonary Hypertension: Side Effects and …

      https://www.healthline.com/health/pulmonary-hypertension/sildenafil-for-pulmonary-hypertension
      When used for this purpose, its known by the brand name Viagra. Sildenafil may also be used to treat pulmonary hypertension (PH). PH is a condition that involves …

    Sildenafil (Viagra) Aggravates the Development of …

      https://www.ahajournals.org/doi/full/10.1161/JAHA.121.023053
      PDE5 inhibitors have been used for treating erectile dysfunction, such as drug Viagra (sildenafil). However, a few clinical cases have reported the association of …

    Sildenafil for Pulmonary Arterial …

      https://journals.lww.com/americantherapeutics/Abstract/2019/08000/Sildenafil_for_Pulmonary_Arterial_Hypertension.15.aspx
      Emergence of new treatments over the past 2 decades has led to improvement in the functional status and time to clinical worsening. Even with recent advances, outcomes …



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