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Unmet medical need - National Institutes of Health

    https://toolkit.ncats.nih.gov/glossary/unmet-medical-need/
    An unmet medical need is a condition or symptom whose treatment or diagnosis is not addressed adequately by available therapy. An unmet medical need includes an …

Unmet Medical Need: An Introduction to Definitions and …

    https://pubmed.ncbi.nlm.nih.gov/31708064/
    Background: Despite increasing informal and formal use of unmet medical need (UMN) in drug development, regulation, and assessment, there is no insight into its definitions in …

Unmet Medical Needs Persist Across Many Diseases

    https://www.forbes.com/sites/joshuacohen/2018/12/26/unmet-medical-needs-persist-across-many-diseases/
    Unmet medical need is defined conventionally in terms of availability and adequacy of treatments, pharmaceutical or otherwise. Treatments may not exist for …

Towards a New Understanding of Unmet Medical Need

    https://link.springer.com/article/10.1007/s40258-021-00655-3
    ‘Unmet medical need’ (UMN) is a central concept in the incentivisation and development of new health technologies, and the identification of a particular medical …

Unmet medical need - EFPIA

    https://efpia.eu/about-medicines/development-of-medicines/unmet-medical-need/
    Unmet medical need should help to shape policy and action from early phase research, through clinical development to pricing and reimbursement to how a new medicine is …

Accelerated Approval Program | FDA

    https://www.fda.gov/drugs/nda-and-bla-approvals/accelerated-approval-program
    A surrogate endpoint is a marker, such as a laboratory measurement, radiographic image, physical sign or other measure that is thought to predict clinical …

Reducing the Economic Burden of Unmet Mental Health …

    https://www.whitehouse.gov/cea/written-materials/2022/05/31/reducing-the-economic-burden-of-unmet-mental-health-needs/
    Mental health disorders cover a broad range of diagnoses, including but not limited to developmental disorders such as Attention Deficit Hyperactivity Disorder …

Patient Perceptions of Unmet Medical Need in …

    https://pubmed.ncbi.nlm.nih.gov/31385264/
    This study aimed to identify and quantify the unmet needs perceived by US patients with RA currently taking a disease-modifying antirheumatic drug (DMARD). Methods: A cross …

Pembrolizumab Could Meet Unmet Need in BCG …

    https://www.cancertherapyadvisor.com/home/news/conference-coverage/american-society-of-clinical-oncology-genitourinary-asco-gu/asco-gu-2023/pembrolizumab-nmibc-high-risk-bcg-unresponsive-unmet-need/
    18 hours ago · This patient population has very limited conventional therapies or clinical trial options and represents an unmet medical need, according to study investigator Andrea …

Antibacterial Therapies for Patients With an Unmet …

    https://www.fda.gov/regulatory-information/search-fda-guidance-documents/antibacterial-therapies-patients-unmet-medical-need-treatment-serious-bacterial-diseases-questions
    Antibacterial Therapies for Patients With an Unmet Medical Need for the Treatment of Serious Bacterial Diseases – Questions and Answers (Revision 1) May …



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