Dictyostelium As A Biomedical Model

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Dictyostelium as a Biomedical Model - Wiley Online Library

https://onlinelibrary.wiley.com/doi/pdf/10.1002/9780470015902.a0006038

The social amoeba, Dictyostelium discoideum, has been commonly used to investigate cell motility, signal transduction, cell type differentiation and development.With the recent completion of the genome and the increasing number of experimental tools …

Dictyostelium discoideum as a non-mammalian …

https://pubmed.ncbi.nlm.nih.gov/33124755/

Dictyostelium discoideum is one of eight non-mammalian model organisms recognized by the National Institute of Health for the study of human pathology. The use of this slime …

Dictyostelium discoideum as a non-mammalian biomedical model

https://ami-journals.onlinelibrary.wiley.com/doi/10.1111/1751-7915.13692

The use of Dictyostelium addresses the development of the principles of the 3Rs in research (replacement, refinement and reduction), to reduce the reliance on the use of …

Dictyostelium: A Tractable Cell and Developmental …

https://www.frontiersin.org/research-topics/16964/dictyostelium-a-tractable-cell-and-developmental-model-in-biomedical-research

For almost a century the social amoeba Dictyostelium discoideum has served as an inexpensive and high-throughput model system for studying a variety of fundamental …

Towards a molecular understanding of human diseases …

https://www.sciencedirect.com/science/article/pii/S1471491406001444

The social amoeba Dictyostelium discoideum is increasingly being used as a simple model for the investigation of problems that are relevant to human health. This …

(PDF) Dictyostelium discoideum: A Model System for …

https://www.researchgate.net/publication/331047933_Dictyostelium_discoideum_A_Model_System_for_Cell_and_Developmental_Biology

Dictyostelium discoideum is a eukaryotic microbe that is used as a biomedical model system for studying a variety of human diseases, including the NCLs (Huber, 2016;Huber et al., 2022). The D ...

Towards a molecular understanding of human diseases …

https://pubmed.ncbi.nlm.nih.gov/16890490/

The social amoeba Dictyostelium discoideum is increasingly being used as a simple model for the investigation of problems that are relevant to human health. This article focuses on …

Dictyostelium discoideum as a pharmacological model …

https://pubmed.ncbi.nlm.nih.gov/31840791/

Developing novel compounds for the treatment of diseases remains one of the highest priorities in biomedical research, where it is critical to identify their targets and …

Dictyostelium - an overview | ScienceDirect Topics

https://www.sciencedirect.com/topics/immunology-and-microbiology/dictyostelium

Several Dictyostelium genes share various degrees of homology and sequence identity to human genes that highlight the importance of this biomedical model system. The …